Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4332
|
Name |
sadC
|
Replicon | chromosome |
Genomic location | 4860248 - 4861711 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 6 transposon mutants in orthologs |
Comment | Overexpression of PA4332 causes increased pellicle formation |
RefSeq | NP_253022 |
GI | 15599528 |
Affymetrix | PA4332_at |
Entrez | 881493 |
GenBank | AAG07720.1 |
NCBI Locus Tag | PA4332 |
protein_id(GenBank) | gb|AAG07720.1|AE004849_7|gnl|PseudoCAP|PA4332 |
TIGR | NTL03PA04333 |
UniProtKB Acc | Q9HW69 |
UniProtKB ID | Q9HW69_PSEAE |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
SadC
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 18.37 |
Kyte-Doolittle Hydrophobicity Value | -0.030 |
Molecular Weight (kDa) | 54.1 |
Isoelectric Point (pI) | 9.87 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4WXO | TRANSFERASE | 11/14/14 | SadC (300-487) from Pseudomonas aeruginosa PAO1 | Pseudomonas aeruginosa PAO1 | 2.805 | X-RAY DIFFRACTION | 100.0 |
4WXW | TRANSFERASE | 11/14/14 | SadC (323-487) from Pseudomonas aeruginosa PAO1 | Pseudomonas aeruginosa PAO1 | 1.8 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 453 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000167 (2758 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4332
Search term: sadC
Search term: SadC
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
The diguanylate cyclase SadC is a central player in Gac/Rsm-mediated biofilm formation in Pseudomonas aeruginosa.
Moscoso JA, Jaeger T, Valentini M, Hui K, Jenal U, Filloux A
J Bacteriol 2014 Dec;196(23):4081-8
PubMed ID: 25225264
|
Specific control of Pseudomonas aeruginosa surface-associated behaviors by two c-di-GMP diguanylate cyclases.
Merritt JH, Ha DG, Cowles KN, Lu W, Morales DK, Rabinowitz J, Gitai Z, O'Toole GA
mBio 2010 Oct 19;1(4)
PubMed ID: 20978535
|
SadC reciprocally influences biofilm formation and swarming motility via modulation of exopolysaccharide production and flagellar function.
Merritt JH, Brothers KM, Kuchma SL, O'Toole GA
J Bacteriol 2007 Nov;189(22):8154-64
PubMed ID: 17586642
|
Synergistic interaction of glyceraldehydes-3-phosphate dehydrogenase and ArsJ, a novel organoarsenical efflux permease, confers arsenate resistance.
Chen J, Yoshinaga M, Garbinski LD, Rosen BP
Mol Microbiol 2016 Jun;100(6):945-53
PubMed ID: 26991003
|