Pseudomonas aeruginosa PAO1, PA4600 (nfxB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
8878035 Reviewed by curator
Biological Process GO:0032410 negative regulation of transporter activity
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
20373734 Reviewed by curator
Molecular Function GO:0000976 transcription regulatory region sequence-specific DNA binding
IDA
Inferred from Direct Assay
ECO:0000096
electrophoretic mobility shift assay evidence
23924707 Reviewed by curator
Molecular Function GO:0000976 transcription regulatory region sequence-specific DNA binding
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
23924707 Reviewed by curator
Biological Process GO:0032410 negative regulation of transporter activity
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
8878035 Reviewed by curator
Biological Process GO:0006355 regulation of transcription, DNA-templated
IDA
Inferred from Direct Assay
ECO:0000002
direct assay evidence

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:1.10.357.10:FF:000022 Transcriptional regulator NfxB - - 5 184 1.0E-109
PANTHER PTHR30055 HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR - - 9 183 4.8E-12
Gene3D G3DSA:1.10.357.10 Tetracycline Repressor, domain 2 - - 5 186 1.4E-27
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 23 79 2.84E-6
SUPERFAMILY SSF48498 Tetracyclin repressor-like, C-terminal domain IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily 81 172 1.13E-12

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.