Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3439
|
Name |
folX
|
Replicon | chromosome |
Genomic location | 3846337 - 3846708 (+ strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_252129.1 |
GI | 15598635 |
Affymetrix | PA3439_folX_at |
DNASU | PaCD00007513 |
Entrez | 877686 |
GenBank | AAG06827.1 |
INSDC | AAG06827.1 |
NCBI Locus Tag | PA3439 |
protein_id(GenBank) | gb|AAG06827.1|AE004764_13|gnl|PseudoCAP|PA3439 |
TIGR | NTL03PA03439 |
UniParc | UPI00000C5A10 |
UniProtKB Acc | Q9HYG7 |
UniProtKB ID | Q9HYG7_PSEAE |
UniRef100 | UniRef100_W0YVQ0 |
UniRef50 | UniRef50_P0AC21 |
UniRef90 | UniRef90_A6V1Y8 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
d-erythro-7,8-dihydroneopterin triphosphate epimerase
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -2.04 |
Kyte-Doolittle Hydrophobicity Value | -0.133 |
Molecular Weight (kDa) | 14.2 |
Isoelectric Point (pI) | 6.11 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4AEY | ISOMERASE | 01/13/12 | Crystal structure of FolX from Pseudomonas aeruginosa | PSEUDOMONAS AERUGINOSA | 3 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 139 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002197 (474 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3439
Search term: folX
|
Dihydroneopterin triphosphate epimerase of Escherichia coli: purification, genetic cloning, and expression.
Haussmann C, Rohdich F, Lottspeich F, Eberhardt S, Scheuring J, Mackamul S, Bacher A
J Bacteriol 1997 Feb;179(3):949-51
PubMed ID: 9006053
|
Purification, cloning, and functional expression of dihydroneopterin triphosphate 2'-epimerase from Escherichia coli.
Ahn C, Byun J, Yim J
J Biol Chem 1997 Jun 13;272(24):15323-8
PubMed ID: 9182560
|
FolX and FolM are essential for tetrahydromonapterin synthesis in Escherichia coli and Pseudomonas aeruginosa.
Pribat A, Blaby IK, Lara-Núñez A, Gregory JF 3rd, de Crécy-Lagard V, Hanson AD
J Bacteriol 2010 Jan;192(2):475-82
PubMed ID: 19897652
|