Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3946
|
Name |
rocS1
Synonym: rocS1 |
Replicon | chromosome |
Genomic location | 4423212 - 4426850 (- strand) |
Transposon Mutants | 6 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 4 transposon mutants in orthologs |
Comment | Overexpression of rocS1 leads to the production of CupB and CupC fimbriae, as well as repression of the MexAB-OprM efflux pump. RocS1 can interact with three response regulators: RocA2 (PA3045), RocA1 (PA3948) and RocR (PA3947). |
RefSeq | NP_252635.1 |
GI | 15599141 |
Affymetrix | PA3946_at |
Entrez | 878870 |
GenBank | AAG07333.1 |
INSDC | AAG07333.1 |
NCBI Locus Tag | PA3946 |
protein_id(GenBank) | gb|AAG07333.1|AE004812_8|gnl|PseudoCAP|PA3946 |
TIGR | NTL03PA03946 |
UniParc | UPI00000C5B8E |
UniProtKB Acc | Q9HX70 |
UniProtKB ID | Q9HX70_PSEAE |
UniRef100 | UniRef100_Q9HX70 |
UniRef50 | UniRef50_W0WA70 |
UniRef90 | UniRef90_W0WA70 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
two-component sensor RocS1
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -26.29 |
Kyte-Doolittle Hydrophobicity Value | -0.058 |
Molecular Weight (kDa) | 134.7 |
Isoelectric Point (pI) | 5.30 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 620 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001586 (824 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3946
Search term: rocS1
Search term: two-component sensor RocS1
|
A novel two-component system controls the expression of Pseudomonas aeruginosa fimbrial cup genes.
Kulasekara HD, Ventre I, Kulasekara BR, Lazdunski A, Filloux A, Lory S
Mol Microbiol 2005 Jan;55(2):368-80
PubMed ID: 15659157
|
Assembly of fimbrial structures in Pseudomonas aeruginosa: functionality and specificity of chaperone-usher machineries.
Ruer S, Stender S, Filloux A, de Bentzmann S
J Bacteriol 2007 May;189(9):3547-55
PubMed ID: 17293418
|
Two-component regulatory systems in Pseudomonas aeruginosa: an intricate network mediating fimbrial and efflux pump gene expression.
Sivaneson M, Mikkelsen H, Ventre I, Bordi C, Filloux A
Mol Microbiol 2011 Mar;79(5):1353-66
PubMed ID: 21205015
|