Pseudomonas aeruginosa PAO1, PA0228 (pcaF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0228
Name
pcaF
Replicon chromosome
Genomic location 257108 - 258313 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248919.1
GI 15595425
Affymetrix PA0228_pcaF_at
Entrez 877715
GenBank AAG03617.1
INSDC AAG03617.1
NCBI Locus Tag PA0228
protein_id(GenBank) gb|AAG03617.1|AE004460_10|gnl|PseudoCAP|PA0228
TIGR NTL03PA00229
UniParc UPI00000C4FAB
UniProtKB Acc Q9I6R0
UniProtKB ID PCAF_PSEAE
UniRef100 UniRef100_Q9I6R0
UniRef50 UniRef50_P0C7L2
UniRef90 UniRef90_Q9I6R0

Product

Feature Type CDS
Coding Frame 1
Product Name
beta-ketoadipyl CoA thiolase PcaF
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -4.96
Kyte-Doolittle Hydrophobicity Value 0.007
Molecular Weight (kDa) 42.1
Isoelectric Point (pI) 5.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 472 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000227 (544 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0228
Search term: pcaF

Human Homologs

Ensembl 94, assembly GRCh38.p12
acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83]
E-value: 1.1e-79
Percent Identity: 42.4

References

Identification of the pcaRKF gene cluster from Pseudomonas putida: involvement in chemotaxis, biodegradation, and transport of 4-hydroxybenzoate.
Harwood CS, Nichols NN, Kim MK, Ditty JL, Parales RE
J. Bacteriol. 1994 Nov;176(21):6479-88
PubMed ID: 7961399