Pseudomonas aeruginosa PAO1, PA1255 (lhpK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1255
Name
lhpK
Replicon chromosome
Genomic location 1363439 - 1364473 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_249946.1
GI 15596452
Affymetrix PA1255_at
DNASU PaCD00006580
Entrez 881287
GenBank AAG04644.1
INSDC AAG04644.1
NCBI Locus Tag PA1255
protein_id(GenBank) gb|AAG04644.1|AE004555_4|gnl|PseudoCAP|PA1255
TIGR NTL03PA01256
UniParc UPI00000C52D1
UniProtKB Acc Q9I489
UniProtKB ID T3HPD_PSEAE
UniRef100 UniRef100_Q9I489
UniRef50 UniRef50_A9CH01
UniRef90 UniRef90_Q9I489

Product

Feature Type CDS
Coding Frame 1
Product Name
D-hydroxyproline epimerase, LhpK
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -4.86
Kyte-Doolittle Hydrophobicity Value -0.152
Molecular Weight (kDa) 37.3
Isoelectric Point (pI) 6.18

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 153 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001206 (835 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1255
Search term: lhpK

Transposon Insertions in PAO1

Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 12443
Genomic Position 1364382
Position in ORF 944(1035)
Reference 14617778
Type ISphoA/hah insertion site
Mutant ID UWGC: 50262
Genomic Position 1364101
Position in ORF 663(1035)
Reference 14617778

Transposon Insertions in Orthologs

References

Molecular characterization of LhpR in control of hydroxyproline catabolism and transport in Pseudomonas aeruginosa PAO1.
Li G, Lu CD
Microbiology (Reading, Engl.) 2016 Jul;162(7):1232-42
PubMed ID: 27145750