Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2080
|
Name |
kynU
|
Replicon | chromosome |
Genomic location | 2289085 - 2290335 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Comment | Genetic evidence, using kynU knockout strain and analyzing PQS production. In ExPASy, this reaction is one of several in the EC #. Listed as kynureninase in NCBI. |
RefSeq | NP_250770.1 |
GI | 15597276 |
Affymetrix | PA2080_at |
Entrez | 877856 |
GenBank | AAG05468.1 |
INSDC | AAG05468.1 |
NCBI Locus Tag | PA2080 |
protein_id(GenBank) | gb|AAG05468.1|AE004635_6|gnl|PseudoCAP|PA2080 |
TIGR | NTL03PA02080 |
UniParc | UPI00000C558F |
UniProtKB Acc | Q9I235 |
UniProtKB ID | Q9I235_PSEAE |
UniRef100 | UniRef100_Q9I235 |
UniRef50 | UniRef50_P83788 |
UniRef90 | UniRef90_Q9I235 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
kynureninase KynU
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -9.73 |
Kyte-Doolittle Hydrophobicity Value | -0.125 |
Molecular Weight (kDa) | 46.3 |
Isoelectric Point (pI) | 5.32 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 361 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003375 (352 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2080
Search term: kynU
Search term: kynureninase KynU
|
Aerobic tryptophan degradation pathway in bacteria: novel kynurenine formamidase.
Kurnasov O, Jablonski L, Polanuyer B, Dorrestein P, Begley T, Osterman A
FEMS Microbiol Lett 2003 Oct 24;227(2):219-27
PubMed ID: 14592712
|
Two distinct pathways supply anthranilate as a precursor of the Pseudomonas quinolone signal.
Farrow JM 3rd, Pesci EC
J Bacteriol 2007 May;189(9):3425-33
PubMed ID: 17337571
|