Pseudomonas aeruginosa PAO1, PA4857 (tspR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4857
Name
tspR
Replicon chromosome
Genomic location 5455434 - 5456027 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253544.1
GI 15600050
Affymetrix PA4857_at
DNASU PaCD00008106
Entrez 877882
GenBank AAG08242.1
INSDC AAG08242.1
NCBI Locus Tag PA4857
protein_id(GenBank) gb|AAG08242.1|AE004899_3|gnl|PseudoCAP|PA4857
TIGR NTL03PA04858
UniParc UPI00000C5E3F
UniProtKB Acc Q9HUV6
UniProtKB ID Q9HUV6_PSEAE
UniRef100 UniRef100_W0YXU7
UniRef50 UniRef50_W0YXU7
UniRef90 UniRef90_W0YXU7

Product

Feature Type CDS
Coding Frame 1
Product Name
TspR
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 7.13
Kyte-Doolittle Hydrophobicity Value 0.961
Molecular Weight (kDa) 21.1
Isoelectric Point (pI) 10.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 374 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004486 (485 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4857
Search term: tspR
Search term: TspR

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Modulation of Type III Secretion System in Pseudomonas aeruginosa: Involvement of the PA4857 Gene Product.
Zhu M, Zhao J, Kang H, Kong W, Liang H
Front Microbiol 2016;7:7
PubMed ID: 26858696