Pseudomonas aeruginosa PAO1, PA4236 (katA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004096 catalase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 10368148 Reviewed by curator
Biological Process GO:0050896 response to stimulus
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0004096 catalase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11465
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006979 response to oxidative stress
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11465
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0042744 hydrogen peroxide catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd08156
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0020037 heme binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11465
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Adaptation, Protection Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc DETOX1-PWY superoxide radicals degradation 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Methane metabolism ECO:0000037
not_recorded
PseudoCAP Tryptophan metabolism ECO:0000037
not_recorded
KEGG pae01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00380 Tryptophan metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00067 Catalase signature IPR018028 Catalase, mono-functional, haem-containing 21 44 2.4E-71
PIRSF PIRSF038928 Catalase_clade1-3 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 1 482 0.0
SUPERFAMILY SSF56634 Heme-dependent catalase-like IPR020835 Catalase superfamily 3 481 0.0
PRINTS PR00067 Catalase signature IPR018028 Catalase, mono-functional, haem-containing 289 316 2.4E-71
PRINTS PR00067 Catalase signature IPR018028 Catalase, mono-functional, haem-containing 84 102 2.4E-71
FunFam G3DSA:2.40.180.10:FF:000001 Catalase - - 3 482 0.0
PRINTS PR00067 Catalase signature IPR018028 Catalase, mono-functional, haem-containing 124 142 2.4E-71
PANTHER PTHR11465 CATALASE IPR018028 Catalase, mono-functional, haem-containing 3 477 0.0
Pfam PF06628 Catalase-related immune-responsive IPR010582 Catalase immune-responsive domain 418 477 1.8E-20
PRINTS PR00067 Catalase signature IPR018028 Catalase, mono-functional, haem-containing 321 347 2.4E-71
Pfam PF00199 Catalase IPR011614 Catalase core domain 8 390 0.0
Gene3D G3DSA:2.40.180.10 Catalase core domain - - 3 482 0.0
CDD cd08156 catalase_clade_3 IPR040333 Catalase, clade 3 48 477 0.0
PRINTS PR00067 Catalase signature IPR018028 Catalase, mono-functional, haem-containing 105 122 2.4E-71
SMART SM01060 Catalase_2 IPR011614 Catalase core domain 8 393 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.