Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2273
|
Name |
soxR
Synonym: soxR |
Replicon | chromosome |
Genomic location | 2503425 - 2503895 (- strand) |
RefSeq | NP_250963.1 |
GI | 15597469 |
Affymetrix | PA2273_at |
Entrez | 882298 |
GenBank | AAG05661.1 |
INSDC | AAG05661.1 |
NCBI Locus Tag | PA2273 |
protein_id(GenBank) | gb|AAG05661.1|AE004653_4|gnl|PseudoCAP|PA2273 |
TIGR | NTL03PA02273 |
UniParc | UPI0000135D19 |
UniProtKB Acc | Q51506 |
UniProtKB ID | SOXR_PSEAE |
UniRef100 | UniRef100_Q51506 |
UniRef50 | UniRef50_Q51506 |
UniRef90 | UniRef90_Q51506 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
SoxR
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 4.56 |
Kyte-Doolittle Hydrophobicity Value | -0.329 |
Molecular Weight (kDa) | 17.0 |
Isoelectric Point (pI) | 8.79 |
Individual Mappings | |
Additional evidence for subcellular localization |
Identified using the Resistance Gene Identifier (RGI)
Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
Pseudomonas aeruginosa soxR | SoxR is a redox-sensitive transcriptional activator that induces expression of a small regulon that includes the RND efflux pump-encoding operon mexGHI-opmD. SoxR was shown to be activated by pyocyanin. [PMID:15845502, PMID:16879411, PMID:27274079] | ARO:3004107 | protein homolog model | Perfect | 309.7 | 100.0 | 3.2.5 |
Source 1 | |
Database | PseudoCAP |
Category | |
Evidence |
ECO:0000314
direct assay evidence used in manual assertion
|
Host Organism | Mus musculus |
Notes | |
Infection model | Mouse pulmonary Infection model |
Reference | 15845502 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 267 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003220 (458 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2273
Search term: soxR
Search term: SoxR
|
Activation of SoxR-dependent transcription in Pseudomonas aeruginosa.
Kobayashi K, Tagawa S
J Biochem 2004 Nov;136(5):607-15
PubMed ID: 15632300
|
Molecular characterization of the soxRS genes of Escherichia coli: two genes control a superoxide stress regulon.
Amábile-Cuevas CF, Demple B
Nucleic Acids Res 1991 Aug 25;19(16):4479-84
PubMed ID: 1653416
|
An iron-sulfur center essential for transcriptional activation by the redox-sensing SoxR protein.
Hidalgo E, Demple B
EMBO J 1994 Jan 1;13(1):138-46
PubMed ID: 8306957
|