Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2889
|
Name |
atuD
|
Replicon | chromosome |
Genomic location | 3242324 - 3243484 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | AtvR is required for P. aeruginosa resistance against macrophage killing, as the deletion of AtvR resulted in higher levels of TNF-_ production and higher levels of bacterial clearance in vitro. |
RefSeq | NP_251579.1 |
GI | 15598085 |
Affymetrix | PA2889_at |
Entrez | 882702 |
GenBank | AAG06277.1 |
INSDC | AAG06277.1 |
NCBI Locus Tag | PA2889 |
protein_id(GenBank) | gb|AAG06277.1|AE004715_3|gnl|PseudoCAP|PA2889 |
TIGR | NTL03PA02889 |
UniParc | UPI00000C5864 |
UniProtKB Acc | Q9HZV8 |
UniProtKB ID | Q9HZV8_PSEAE |
UniRef100 | UniRef100_W0YUM8 |
UniRef50 | UniRef50_B6RA10 |
UniRef90 | UniRef90_Q4K8Z4 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
citronellyl-CoA dehydrogenase, AtuD
|
Synonyms |
putative citronellyl-CoA dehydrogenase involved in catabolism of citronellol |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -2.78 |
Kyte-Doolittle Hydrophobicity Value | -0.152 |
Molecular Weight (kDa) | 42.7 |
Isoelectric Point (pI) | 6.27 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 460 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002684 (403 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2889
Search term: atuD
Search term: citronellyl-CoA dehydrogenase, AtuD
|
Ensembl
110, assembly
GRCh38.p14
|
acyl-CoA dehydrogenase short chain [Source:HGNC Symbol;Acc:HGNC:90]
E-value:
2.4e-62
Percent Identity:
35.5
|
Identification of genes and proteins necessary for catabolism of acyclic terpenes and leucine/isovalerate in Pseudomonas aeruginosa.
Förster-Fromme K, Höschle B, Mack C, Bott M, Armbruster W, Jendrossek D
Appl Environ Microbiol 2006 Jul;72(7):4819-28
PubMed ID: 16820476
|
2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans.
Wilson R, Ainscough R, Anderson K, Baynes C, Berks M, Bonfield J, Burton J, Connell M, Copsey T, Cooper J
Nature 1994 Mar 3;368(6466):32-8
PubMed ID: 7906398
|
Biochemical characterization of AtuD from Pseudomonas aeruginosa, the first member of a new subgroup of acyl-CoA dehydrogenases with specificity for citronellyl-CoA.
Förster-Fromme K, Chattopadhyay A, Jendrossek D
Microbiology (Reading) 2008 Mar;154(Pt 3):789-796
PubMed ID: 18310025
|
The Atypical Response Regulator AtvR Is a New Player in Pseudomonas aeruginosa Response to Hypoxia and Virulence.
Kaihami GH, Breda LCD, de Almeida JRF, de Oliveira Pereira T, Nicastro GG, Boechat AL, de Almeida SR, Baldini RL
Infect Immun 2017 Aug;85(8)
PubMed ID: 28533471
|