Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5410
|
Name |
gbcA
Synonym: gbcA |
Replicon | chromosome |
Genomic location | 6085385 - 6086674 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 4 transposon mutants in orthologs |
Comment | Strains with deletions in gbcA are unable to grow on choline or glycine betaine but are able to grow on dimethylglycine. NMR analysis shows buildup of labeled glycine betaine when gbcA mutants are givenlabeled choline. |
RefSeq | NP_254097.1 |
GI | 15600603 |
Affymetrix | PA5410_at |
Entrez | 880240 |
GenBank | AAG08795.1 |
INSDC | AAG08795.1 |
NCBI Locus Tag | PA5410 |
protein_id(GenBank) | gb|AAG08795.1|AE004953_9|gnl|PseudoCAP|PA5410 |
TIGR | NTL03PA05411 |
UniParc | UPI00000C5FEF |
UniProtKB Acc | Q9HTF4 |
UniProtKB ID | Q9HTF4_PSEAE |
UniRef100 | UniRef100_W0Z2H4 |
UniRef50 | UniRef50_W9VLP0 |
UniRef90 | UniRef90_A0A024HQV1 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
GbcA
|
Synonyms |
glycine betaine catabolism protein GbcA |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -7.41 |
Kyte-Doolittle Hydrophobicity Value | -0.385 |
Molecular Weight (kDa) | 48.7 |
Isoelectric Point (pI) | 6.20 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 192 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003046 (1308 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5410
Search term: gbcA
Search term: GbcA
|
Identification of two gene clusters and a transcriptional regulator required for Pseudomonas aeruginosa glycine betaine catabolism.
Wargo MJ, Szwergold BS, Hogan DA
J Bacteriol 2008 Apr;190(8):2690-9
PubMed ID: 17951379
|