Pseudomonas aeruginosa PAO1, PA3045 (rocA2)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0051051	negative regulation of transport	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	21205015	Reviewed by curator
Molecular Function	GO:0000156	phosphorelay response regulator activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	15659157	Reviewed by curator
Biological Process	GO:0006355	regulation of transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00038	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0000160	phosphorelay signal transduction system	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00448	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Two-component System		ECO:0000037 not_recorded
KEGG	pae02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF00196	Bacterial regulatory proteins, luxR family	IPR000792	Transcription regulator LuxR, C-terminal	147	201	5.2E-21
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	147	161	4.9E-12
Pfam	PF00072	Response regulator receiver domain	IPR001789	Signal transduction response regulator, receiver domain	4	115	5.2E-26
SMART	SM00448	REC_2	IPR001789	Signal transduction response regulator, receiver domain	2	114	4.0E-30
SUPERFAMILY	SSF52172	CheY-like	IPR011006	CheY-like superfamily	2	170	2.85E-30
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	177	189	4.9E-12
Gene3D	G3DSA:3.40.50.2300	-	-	-	3	207	5.6E-52
FunFam	G3DSA:3.40.50.2300:FF:000267	Virulence factors transcription regulator	-	-	3	207	3.1E-126
PANTHER	PTHR45566	HTH-TYPE TRANSCRIPTIONAL REGULATOR YHJB-RELATED	-	-	2	200	2.6E-36
CDD	cd06170	LuxR_C_like	IPR000792	Transcription regulator LuxR, C-terminal	147	203	2.33132E-18
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	161	177	4.9E-12
SMART	SM00421	luxrmega5	IPR000792	Transcription regulator LuxR, C-terminal	144	201	1.3E-21
CDD	cd17535	REC_NarL-like	-	-	4	119	4.66935E-42

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.